Impact of a New Zealand berry fruit product on lung health and immunological status of individuals living in urban China

Not Applicable

Withdrawn

• Conditions: Respiratory disease; Systemic inflammation; Public Health - Other public health; Diet and Nutrition - Other diet and nutrition disorders; Respiratory - Normal development and function of the respiratory system; Inflammatory and Immune System - Normal development and function of the immune system

• Registration Number: ACTRN12619001736134
• Lead Sponsor: Malaghan Institute of Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-12-09
• Last Update Posted: 14 June 2021

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 110

Inclusion Criteria

Participants must meet all the following criteria:
a.Male of female
b.Chinese ethnicity
c.Age is between 30 and 70 years
d.Body mass index (BMI) between 18 and 35 kg/m2
e.Self-reported as healthy
f.Catch public transport daily or occupationally exposed to airborne particulate emission for at least 2 hours on a daily basis

Exclusion Criteria

Participants with at least one of the following criteria will be excluded:
a.BMI < 18 kg/m2 or BMI > 35 kg/m2
b.Chronic obstructive pulmonary disease (COPD), or other chronic respiratory condition (including sleep apnoea)
c.Cardiovascular disease (CVD), including current angina; myocardial infarction or stroke within the past 6 months; heart failure; symptomatic peripheral vascular disease; SBP > 160 mmHg and/or DBP > 100 mmHg (with or without hypertensive medication)
d.Type 1 or type 2 diabetes mellitus
e.Chronic renal impairment; liver disease e.g. cirrhosis; prior bariatric surgery, neurological, psychiatric, or musculoskeletal disease
f.Autoimmune disease, including rheumatoid arthritis, systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD), celiac disease, pancreatitis or other malabsorption condition.
g.Malignancy
h.Recent prior (previous 4 weeks) or current use of antibiotics
i.Recent prior (previous 4 weeks) or current respiratory infection
j.Current or prior eating disorder (e.g. anorexia nervosa, bulimia)
k.Food allergy or intolerance that would compromise compliance with the study protocol, including berry fruits and apples
l.Pregnant or breastfeeding; or intent to become pregnant during study duration
m.Current participation in another clinical intervention study
n.Inability to provide written informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified