The Impact of Inspiratory Muscle Strength Training

Not Applicable

Completed

• Conditions: Ventilator Dependency
• Interventions: Device: inspiratory muscle strength training

• Registration Number: NCT03997214
• Lead Sponsor: Fooyin University

Brief Summary

The study is a pre-post test with quasi experimental design. Forty-two intubated-adults who had been mechanically ventilated for more than 21 days were selected on the basis of inclusion criteria in respiratory care ward. These patients were classified equally into study group and control group. The experimental group received the intervention of respiratory muscles training 5 times/ a week for 6 weeks. The control group received normal care. The intervention was adjusted trigger sensitivity to 10% of the first recorded Maximal Inspiratory Pressure at the start of training, then increased the ventilator trigger sensitivity and training duration weekly. The largest of ventilator trigger sensitivity is not over 40% of the initial Maximal Inspiratory Pressure and the timing of training duration is no longer than 30 minutes.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-06-15
• Primary Completion: 2018-12-30
• Study Completion: 2018-12-31
• Status Verified: 2019-05
• Study First Submitted: 2019-06-04
• Study First Submitted QC: 2019-06-21
• Last Update Submitted: 2019-06-21
• Study First Posted: 2019-06-25
• Last Update Posted: 2019-06-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 43

Inclusion Criteria

• Age >20y/o
• Vital signs stable
• MIP <20cmH2O
• Ventilator FiO2<40%, PEEP <8
• Ventilator mode:PSV or SIMV

Exclusion Criteria

• Patient or family refuse

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
experimental group	inspiratory muscle strength training	The intervention of inspiratory muscle strength training

Primary Outcome Measures

Name	Time	Method
Minute ventilation volume	7 weeks	the quantity of air moved into and out of the lungs in a minute, measurement by l.min
Oxygenation index.	7 weeks	Oxygenation index OI = FiO2 x 100 x M AP/PaO2, where FiO2 is the fraction of inspired oxygen, MAP is the mean airway pressure, and PaO2 is the partial pressure of oxygen in arterial blood, calculated at the end of the first day of standardized preoperative stabilization
Maximal inspiratory pressure	7 weeks	a measure of the strength of inspiratory muscles, measurement by cmH2O.
Rapid shallow breathing index	7 weeks	the ratio of respiratory frequency to tidal volume (f/VT)
Tidal volume	7 weeks	the volume of air that is transported into and out of the lungs with each respiratory cycle, measurement by mL per inspiration

Trial Locations

Locations (1)

Shinghou Hospital; 🇨🇳 Kaohsiung, Fengshan, Taiwan