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临床试验/NCT03997214
NCT03997214已完成不适用

The Impact of Inspiratory Muscle Strength Training on Weaning Parameters Among Ventilator-dependent Patients

Fooyin University2 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2018年6月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
43
试验地点
2
主要终点
Minute ventilation volume

研究概览

简要总结

The study is a pre-post test with quasi experimental design. Forty-two intubated-adults who had been mechanically ventilated for more than 21 days were selected on the basis of inclusion criteria in respiratory care ward. These patients were classified equally into study group and control group. The experimental group received the intervention of respiratory muscles training 5 times/ a week for 6 weeks. The control group received normal care. The intervention was adjusted trigger sensitivity to 10% of the first recorded Maximal Inspiratory Pressure at the start of training, then increased the ventilator trigger sensitivity and training duration weekly. The largest of ventilator trigger sensitivity is not over 40% of the initial Maximal Inspiratory Pressure and the timing of training duration is no longer than 30 minutes.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

入排标准

性别
All
接受健康志愿者

入选标准

  • Age >20y/o
  • Vital signs stable
  • MIP <20cmH2O
  • Ventilator FiO2<40%, PEEP <8
  • Ventilator mode:PSV or SIMV

排除标准

  • Patient or family refuse

研究组 & 干预措施

Control group

No Intervention

as usual care

experimental group

Experimental

The intervention of inspiratory muscle strength training

干预措施: inspiratory muscle strength training (Device)

结局指标

主要结局

Minute ventilation volume

时间窗: 7 weeks

the quantity of air moved into and out of the lungs in a minute, measurement by l.min

Oxygenation index.

时间窗: 7 weeks

Oxygenation index OI = FiO2 x 100 x M AP/PaO2, where FiO2 is the fraction of inspired oxygen, MAP is the mean airway pressure, and PaO2 is the partial pressure of oxygen in arterial blood, calculated at the end of the first day of standardized preoperative stabilization

Maximal inspiratory pressure

时间窗: 7 weeks

a measure of the strength of inspiratory muscles, measurement by cmH2O.

Rapid shallow breathing index

时间窗: 7 weeks

the ratio of respiratory frequency to tidal volume (f/VT)

Tidal volume

时间窗: 7 weeks

the volume of air that is transported into and out of the lungs with each respiratory cycle, measurement by mL per inspiration

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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