Prognostic Value of Systemic Immun Inflamation Index in Geriatrik Patient Admitted to the ICU After Surgery: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 150
- 主要终点
- Measuring the Systemic Immune-Inflammation Index (SII) in postoperative patients to see the parameter's predictibility of 30-day mortality
研究概览
简要总结
The Systemic Immuno-Inflammation Index (SII) is a ratio derived from complete blood count parameters (neutrophils, lymphocytes, platelets) and is a non-invasive and easily calculable biomarker. The SIPI effectively reflects both local and systemic inflammatory responses in the human body. It has been used to predict and evaluate the prognosis of various solid tumors such as gastric cancer, non-small cell lung cancer, and colorectal cancer. Furthermore, the SIPI has been shown to have significant prognostic value in cardiovascular and cerebrovascular diseases. In this study, the SIPI will be calculated using laboratory data at the time of admission to the intensive care unit, and the relationship between the obtained values and the 30-day mortality status of the patients will be analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient must be 65 years of age or older (in the geriatric age group),
- •Admitted to the intensive care unit after elective or emergency surgery
- •Have access to complete blood count (hemogram) data (neutrophils, lymphocytes, platelets) during their stay in the intensive care unit
- •Be able to undergo 30-day mortality monitoring from the date of admission to the intensive care unit
- •Have provided informed consent from the patient or their legal representative.
排除标准
- •Patients under 65 years of age
- •Patients admitted to the intensive care unit for non-surgical reasons (e.g., trauma, medical intensive care indications)
- •Patients with deficient neutrophil, lymphocyte, or platelet counts upon admission to the intensive care unit
- •Patients with a history of malignancy, hematological disease, or immunosuppressive therapy
- •Terminally ill palliative patients
- •Patients who refuse informed consent.
结局指标
主要结局
Measuring the Systemic Immune-Inflammation Index (SII) in postoperative patients to see the parameter's predictibility of 30-day mortality
时间窗: Postoperative day 1
In geriatric patients admitted to the intensive care unit after surgery, the Systemic Immune-Inflammation Index (SII) is a significant biomarker for predicting 30-day mortality.
次要结局
未报告次要终点
研究者
Leman Acun Delen
Associate Professor
Malatya Egitim Ve Arastirma Hastanesi