The influence of a proanthocyanidin-enriched herbal extract from Rumex acetosa L. on the intraoral colonization with Porphyromonas gingivalis
Not Applicable
- Conditions
- K05.3Chronic periodontitis
- Registration Number
- DRKS00005654
- Lead Sponsor
- Heinrich-Heine-Universität DüsseldorfMedizische Fakultät
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
generally healthy
periodontally healthy with Periodontal Screening Index = 2
Exclusion Criteria
-antibiotic therapy within the previous 6 months
-allergies against mouthrinse components
-pregnancy or lactation
-soft tissue lesions (e.g. lichen planus, leukoplakia)
-history of periodontal disease and/ or PSI = 3 or more
-any topical or systemical medication, that potentially influence any immunological parameters
-any systemic disease or medical condition (e.g. diabetes or immunological disorders), that potentially influence the immune response or compromise the study results
-any systemic conditions, that require an antibiotic coverage for routine dental procedures (e.g. endocarditis)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method