asal ventilation strategies in preterm babies with respiratory distress syndrome
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Respiratory distress syndrome
- Registration Number
- CTRI/2014/01/004284
- Lead Sponsor
- KEM Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 63
Inclusion Criteria
Preterm very low birth weight infants admitted to the neonatal intensive care unit with respiratory distress and chest X-ray suggestive of RDS on mechanical ventilation
Exclusion Criteria
Infants having nasopharyngeal pathology e.g. choanal atresia, cleft lip or palate, major / lethal congenital anomalies, severe intraventricular haemorrhages were excluded
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare efficacy of NIPPV versus NCPAP as post-extubation respiratory support in infants with RDS, in terms of respiratory failure defined by respiratory acidosis, increased oxygen requirement or apnea requiring ventilatory support during first 72 hours post-endotracheal extubation. <br/ ><br> <br/ ><br>Timepoint: 72 hours <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.To compare the duration of noninvasive ventilation in the two groups. <br/ ><br>2.To compare the duration of supplementary oxygen requirement in the two groups in hours post extubation. <br/ ><br>3.To compare the two groups in terms of rates of bronchopulmonary disease. <br/ ><br>4.To compare the two groups in terms of mortality, duration of hospital stay, incidence of complications, duration of mechanical ventilation including non invasive support <br/ ><br> <br/ ><br>Timepoint: 1. For Bronchopulmonary dysplasia: At 36 weeks <br/ ><br>2. Mortality: Before discharge from NIC