The protective effect of Guanxinning on panvascular disease in patients with stable angina pectoris
- Conditions
- Stable coronary heart disease
- Registration Number
- ITMCTR2200005556
- Lead Sponsor
- Hangzhou Hospital of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
At the same time, it meets the above-mentioned diagnostic criteria for stable coronary heart disease and TCM heart and blood stasis syndrome. Coronary angiography or treadmill exercise test confirms that they are between 30 and 80 years old to participate in this test voluntarily and sign an informed consent form.
?Patients with unstable angina; ?Combined with acute infection, uncontrolled grade ? hypertension (systolic blood pressure =180mmHg and/or diastolic blood pressure =110mmHg), severe cardiopulmonary insufficiency (heart function grade ?, ?, severe pulmonary insufficiency) , Severe arrhythmia, severe diseases (such as tumors, etc.) and mental illness that affect their survival; ?Recently (6 months) with severe bleeding disease, active bleeding or surgical history; ?Within the past 1 month Patients with acute cerebral infarction and other traumatic brain injuries; ?platelet count <50×10 9 /L, hematocrit 30%; ? abnormal liver and kidney function indexes (ALT and AST exceed the upper limit of the normal reference range by 2 times, Ccr is low Less than 30ml/(min*1.73m2)); ?Patients who are allergic to the test drug (including its ingredients); ?Patients with pregnancy plans or pregnant or lactating women; ?Patients who have participated in other clinical trials within the past 1 month ; ? Alcoholism or drug addicts.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Angina Pectoris TCM Syndrome Score;
- Secondary Outcome Measures
Name Time Method Coronary plaque changes;Heart function;Carotid plaque changes;Changes in physical and chemical indicators;Changes in inflammatory factors;