Post-operative pulmonary complications after major abdominal surgery

Phase 3

Not yet recruiting

Conditions: Disease of stomach and duodenum, unspecified,

Registration Number: CTRI/2020/11/028841

Lead Sponsor: Dr Poorva pramod more

Brief Summary: In this study patients who are posted for elective or emergency major abdominal surgery, satisfying all inclusion and exclusion criteria,will be included.All patients or their next of kin will be explained about the study and a written valid informed consent for their willingness to participate in the study will be taken.

This will be a pragmatic study with no change in routine clinical practice.The choice of anaesthetic agents, muscle relaxants,perioperative analgesia will be decided by anesthesiologist conducting the case.The decision regarding extubation and poste operative management will be taken by the anesthesiologist and surgeons as per routine clinical or practice

The baseline characteristics including age of patient,ASA grading,sex will be noted

During intraoperative period technique of ventilation, ventilator settings will be noted, intraoperative hypotension and desaturation and administration of unplanned vasoactive drugs will be recorded.

PPCs will be clinically observed and recorded daily from day of surgery until discharge from hospital or until postoperative day 7 whichever comes first.Each adverse pulmonary event will be recorded dail.Length of hospital stay and in hospital mortality will be determined from patients records or telephonically at postoperative day 30

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 400

Inclusion Criteria

All adult patients who undergo elective or emergency major abdominal surgery under GA or GA and RA.

Exclusion Criteria

1 patient not consenting 2 younger tajn 18years 3 obstetric procedure or any procedure during pregnancy 4 procedures related to previous surgical complications 5 organ transplantation.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To find out the incidence of PPC in patients undergoing major abdominal surgery.	4 week
2.To find factors associated with the development of PPC after major abdominal surgery	4 week

Secondary Outcome Measures

Name	Time	Method
1Assessment and comparison of ARISCAT and LAS VEGAS score in predicting PPC	2 In- hospital mortality due to PPC

Trial Locations

Locations (1): Lokmanya Tilak Muncipal Medical College and GeneralHospital
🇮🇳
Mumbai, MAHARASHTRA, India
Lokmanya Tilak Muncipal Medical College and GeneralHospital
🇮🇳Mumbai, MAHARASHTRA, India
Dr Poorva pramod more
Principal investigator
9167645894
poorvamore.pm@gmail.com