affect of curcumin on oral mucosa evaluated histopathologically in Leukoplakia cases

Phase 1

• Conditions: Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue

• Registration Number: CTRI/2023/09/057594
• Lead Sponsor: Sharda University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

oral leukoplakia

Exclusion Criteria

any other white lesion of oral cavity

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To observe changes in oral mucosa in cases of oral Leukoplakia by performing a biopsy to see histopathological changes after administration of curcumin capsules for 3 monthsTimepoint: To observe changes in oral mucosa in cases of oral Leukoplakia by performing a biopsy to see histopathological changes after administration of curcumin capsules for 3 months

Secondary Outcome Measures

Name	Time	Method
to see changes in oral mucosa after intake of curcumin for 3 months in cases of oral Leukoplakia, histopathologically & clinically. Since OLP is PMDTimepoint: to see changes on a clinical basis size of the lesion, mouth opening, pain & burning sensation on a monthly basis. Secondly to evaluate histopathologically after 2nd Biospy changes in mucosa after curcumin treatment (Dysplasia decreased or increased)