Reference Diameter and Characteristics of Distal Radial Artery by Ultrasonographic Assessement in Korean Patients

Completed

• Conditions: Radial Artery
• Interventions: Procedure: Ultrasonography

• Registration Number: NCT04303923
• Lead Sponsor: Wonju Severance Christian Hospital

Brief Summary

Radial access is recommended as the standard approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI) based on the evidence in which RA reduced mortality and bleeding events compared with femoral access. Recently, the use of distal radial artery (DRA) is rapidly increasing in accordance with the publication of several studies that have shown easy hemostasis, reduced bleeding complications and low arterial occlusion rate via distal radial approach. However, the diameter of DRA is relatively smaller than radial artery (RA) which can limit the widespread use of this access route. Regarding the size discrepancy, there is a lack of evidence to guide which patients are acceptable or not for CAG and PCI. Therefore, the main purpose of this study was to provide the reference diameter of DRA using ultrasonography in Korean patients. The clinical predictors for small DRA also were evaluated.

Detailed Description

Radial access is recommended as the standard approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI) based on the evidence in which RA reduced mortality and bleeding events compared with femoral access. Recently, the use of distal radial artery (DRA) is rapidly increasing in accordance with the publication of several studies that have shown easy hemostasis, reduced bleeding complications and low arterial occlusion rate via distal radial approach. However, the diameter of DRA is relatively smaller than radial artery (RA) which can limit the widespread use of this access route. Regarding the size discrepancy, there is a lack of evidence to guide which patients are acceptable or not for CAG and PCI. Therefore, the main purpose of this study was to provide the reference diameter of DRA using ultrasonography in Korean patients. The clinical predictors for small DRA also were evaluated.

Assessment of arterial diameter by ultasonography Patients were lying on the bed with relaxation in an quiet room. The outer diameters of both DRA and RA were assessed by a perpendicular angle using a linear ultrasound probe (3-4-10.8 MHz) and the average values were recorded. The diameter of RA was measured from 2-3 cm above wrist crease. Anatomical landmark for the measurement of DRA was the bony surface area just distal space from extensor pollicis longus tendon in which the DRA was best palpable then runs down between the first metacarpal and second metacarpal bone (just out of anatomical snuffbox area)

Study Timeline

• Study Start: 2017-07-07
• Primary Completion: 2018-04-13
• Study Completion: 2020-02-29
• Status Verified: 2020-03
• Study First Submitted: 2020-03-09
• Study First Submitted QC: 2020-03-09
• Last Update Submitted: 2020-03-10
• Study First Posted: 2020-03-11
• Last Update Posted: 2020-03-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1162

Inclusion Criteria

• Patients planned to perform transthoracic echocardiography with arterial ultrasonography

Exclusion Criteria

• Age under 20-year
• Poor image quality
• repeated measurement

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Male group	Ultrasonography	Male patients who performed transthoracic echocardiography with arterial ultrasonography
Female group	Ultrasonography	Female patients who performed transthoracic echocardiography with arterial ultrasonography

Primary Outcome Measures

Name	Time	Method
The diameter of distal radial artery	Through ultrasonographic evaluation (within 1 hour)	Mean diameter of distal radial artery on both left and right hand

Secondary Outcome Measures

Name	Time	Method
The diameter of radial artery	Through ultrasonographic evaluation (within 1 hour)	Mean diameter of radial artery on both left and right hand
Predictor for small distal radial artery	Through ultrasonographic evaluation (within 1 hour)	Clinical predictor associated with small distal radial artery
Arterial diameter index	Through ultrasonographic evaluation (within 1 hour)	Diameter of measure artery divided by body surface area
Proportion of small distal radial artery	Through ultrasonographic evaluation (within 1 hour)	Proportion of small distal radial artery (\<2.3mm)

Trial Locations

Locations (1)

Wonju Severance Christian Hospital; 🇰🇷 Wonju, Gangwon-do, Korea, Republic of