Decrease Artery Occlusion by Distal Radial Arterial Cannulation, Observational Study

• Conditions: Outcome, Fatal; Procedural Complication; Acute Coronary Syndrome
• Interventions: Procedure: Radial Artery Approach

• Registration Number: NCT05230719
• Lead Sponsor: Shenzhen People's Hospital

Brief Summary

The site of arterial access for coronary angiography and intervention has been the focus of research for decades as it is the source of major complications. Transradial access (TRA) reduces complications among patients undergoing percutaneous coronary procedures but is reported with the complication of radial artery occlusion (RAO) that limits the radial artery for future needs. Distal radial access (dTRA) has recently gained global popularity as an alternative access route for vascular procedures. Among the benefits of dTRA are the low risk of entry site bleeding complications, the low rate of radial artery occlusion, and improved patient and operator comfort. This study aims to reveal the feasibility and safety of dTRA and routine TRA procedures in acute coronary syndrome patients. The primary endpoints are forearm radical occlusion rate and major adverse cardiovascular events (MACEs) in the two groups. Investigators conduct this retrospected analysis to demonstrate the difference of the two procedure of Cannulation.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-01
• Status Verified: 2022-01
• Study First Submitted: 2022-01-19
• Study First Submitted QC: 2022-01-29
• Study First Posted: 2022-02-09
• Last Update Submitted: 2022-02-11
• Last Update Posted: 2022-03-02
• Primary Completion: 2024-01-01
• Study Completion: 2024-01-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

• presence of a pulse in the snuffbox

Exclusion Criteria

• Absence of pulse
• Ultrasound indication of arterial occlusion or severe calcification
• Severe forearm artery malformation
• Patients with severe liver and renal failure, or abnormal coagulation function
• Established cardiogenic shock
• History of previous coronary artery bypass grafting and radial artery use.
• Raynaud's disease in the medical history

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
TRA group	Radial Artery Approach	Investigators perform percutaneous coronary intervention by conventional TRA for patients
dTRA group	Radial Artery Approach	Investigators perform percutaneous coronary intervention by dTRA for patients

Primary Outcome Measures

Name	Time	Method
Forearm radical	2 years	Doppler ultrasound to determine whether patients suffer forearm radial occlusion
MACEs	2 years	Major Adverse Cardiovascular Events, including cardiovascular death, myocardial infarction and heart failure.

Trial Locations

Locations (1)

Shenzhen People's hospital; 🇨🇳 Shenzhen, Guangdong, China