EUCTR2014-002239-33-BE进行中（未招募）1 期
The effect of corticotrophin-releasing hormone (CRH) on esophageal motility in healthy volunteers - The effect of CRH on esophageal motility
TARGID, KU Leuven0 个研究点目标入组 14 人开始时间: 2014年8月29日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 14
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Healthy volunteers aged between 18-60 years
- •No history of gastrointestinal symptoms or complaints.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1. history of allergic reaction to CRH,
- •2.atopy (eczema, asthma, food allergies, allergic rhinoconjunctivis) or
- •multiple allergies to several drugs,
- •3. pregnancy or lactation,
- •4.concomitant administration of monoamine oxidase inhibitors (MAOI),
- •verapamil or diltiazem or medication affecting esophageal motility,
- •5. significant co-morbidities (neuromuscular, psychiatric, cardiovascular,
- •pulmonary, endocrine, autoimmune, renal and hepatic),
- •6. prior history of esophageal, ENT or gastric surgery or endoscopic antireflux
- •procedure, history of gastrointestinal disease and first degree
- •relatives with Crohn's disease or celiac disease.
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