IRCT20221207056746N1招募中2 期
Comparing the analgesic effect of single-dose preoperative administration of noblegin, celecoxib and advalgin ER on demand for next dose of analgesic in mandibular third molar surgery
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 15 years 至 29 years（—）
- 性别
- All
入选标准
- •Healthy patients (ASA class I)
- •Candidates of prophylactic removal of mandibular third molar,full or partial bony impaction confirmed by panoramic X-ray
- •Requiring soft tissue flap, bone manipulation and bone removal
- •No medication consumption in the past 21 days
- •The presence of the first and second molars
- •Good oral hygiene
- •Absence of pericoronitis or inflammation signs
- •Absence of local or systemic infection
排除标准
- •Pregnant or breastfeeding women or women of child bearing potential not using adequate contraception
- •Allergy or hypersensitivity to study treatments, rescue medication (rm) or any other nsaids, opioids and acetyl salicylic acid
- •History of NSAID-sensitive asthma
- •History of or the suspicion of drug or alcohol abuse
- •Apical radiolucent image in target tooth
- •Consmuption of central nervous system depressants
- •Pre-existing pain and acute inflammation
- •Inability to understand or perform the study procedure
- •Consumption of caffeine-containing beverages, chocolate, or alcohol within 4 hours prior to surgery
- •Oral contraception use
- •Being in the menstrual period
- •Any contraindication of cox-2 inhibitors use
研究者
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