Comparison of preemptive analgesic effect of Naproxen, Celecoxib and Acetaminophen codeine on pain control after mandibular third molar surgery

Phase 2

Conditions: Control of pain after third molar surgery.
Injury, poisoning and certain other consequences of external causes

Registration Number: IRCT20190615043899N1

Lead Sponsor: Boushehr University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 78

Inclusion Criteria

Patient OPG to confirm that the hardness of the lower third molar is the same.
Patient-patient pain rating
History of systemic diseases
Patient should not have a history of hypersensitivity to steroid drugs
Patient in the range of 18 to 60 years old
Avoid taking an hour before taking analgesic
A person can read and understand the checklist
The patient does not take analgesic because of chronic pain

Exclusion Criteria

There is an infection of the postoperative dry socket
Diabetic patients
Systemic drug interactions with the three drugs in this study
Use of psychological drugs
The presence of rotting teeth or needing treatment in the mouth
Lack of cooperation for future referrals
Systemic disease
People who had started treating the wound of the gastrointestinal tract for 30 days before surgery
Used analgesics or another drug for 24 hours before surgery
History of narcotic or analgesic addiction
Patients who were pregnant or Breastfeeding
Known sensitivity to anti-inflammatory drugs, non-steroidal anti-inflammatory drugs ordinary or cyclooxygenase-2 inhibitors

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of pain. Timepoint: The severity of pain was the patient who was recorded in the questionnaire during the prescribed hours (7 days and 72, 48, 24, 12, 8, 4). Method of measurement: The severity of pain was as follows: the patient, based on her sense of pain, determined a number between 10-1 according to the definition of the pain states based on the degree of discomfort / pain. The number 1 indicates that the patient feels good and does not feel pain, and the number 10 indicates a painful pain, to the extent that the patient leaves all his work and feels the need for rest.

Secondary Outcome Measures