Comparison Between Two Techniques of Volemic Expansion in Hip Replacement Arthroplasty
- Conditions
- Hip Replacement Arthroplasty
- Interventions
- Drug: Ringer's lactate
- Registration Number
- NCT00542516
- Lead Sponsor
- University of Sao Paulo
- Brief Summary
Currently the most use solution to volemic reposition in hip replacement arthroplasty is the crystalloid solution. This trial intends to compare two different volemic replacements: HES and Ringer's lactate. This research has been analyzing hemodynamic parameters and the coagulation status before and after the pre-expansion with the solutions above mentioned.
- Detailed Description
This trial is randomized an blind to the physician who is analyzing the results.It has been select adults; both sex; ASA I and II. These patients must be submitted to hip arthroplasty replacement. The anesthesia technique is single shot spinal anesthesia. Primary endpoint: assessment alternative; technique replacement volemic with HES 130/04. Secondary endpoint: haemostatic abnormalities; blood loss; transfusion blood.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- Patients involved: adults, ASA I and II;
- Surgery: hip replacement arthroplasty.
- Allergy starch;
- Anemia;
- Dysfunction renal;
- Heart insufficiency;
- Morbid obesity.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ringer's lactate Ringer's lactate Pre-expansion with Ringer's lactate HES 130/04 Hydroxyethyl Starch Pre-expansion with HES Ringer's lactate Hydroxyethyl Starch Pre-expansion with Ringer's lactate
- Primary Outcome Measures
Name Time Method HES expansion plasmatic efficacy 24 hours
- Secondary Outcome Measures
Name Time Method Blood transfusion 24 hours Haemostatic alterations 24 hours
Trial Locations
- Locations (1)
Institute of Orthopedics and Traumatology of HCFMUSP
🇧🇷São Paulo, Brazil