The effects of nitrous oxide on psychosis-like and psychedelic experiences in healthy volunteers: a single-blind randomized experimental study

niversity College London0 个研究点目标入组 80 人开始时间: 2019年8月28日最近更新: 2021年8月24日

试验速览

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33667308/ (added 13/08/2021)

•1.Age: 18-40
•2.Fluency in written and spoken English
•3.Consumes alcohol as social drinker
•4.For hypothesis related to moderation of subjective effects by bipolar phenotype, participants will be high scores (>=7) on the Mood Disorder Questionnaire

•1. Are pregnant or are likely to become pregnant during the study or breastfeeding.
•2. Suffer from any major physical health disorder
•3. Are currently seeking/receiving treatment for any psychiatric condition
•4. Have asthma or any breathing difficulty (including sleep apnoea)
•5. Have a cardiovascular condition or a fitted pacemaker
•6. Have any liver or kidney disorder
•7. Have had a ‘collapsed lung’
•8. Have difficulties metabolising vitamin B12
•9. Have anaemia
•10. Have history of stomach ulcers
•11. Have high or low blood pressure
•12. Have a current ear or sinus infection or a bad cold
•13. Have epilepsy
•14. Have ever had neurosurgery
•15. Are diabetic
•16. Have had any recent dental work or dental infection/inflammation
•17. Have had any adverse reaction to nitrous oxide in the past
•18. Use recreational drugs more than once a week
•19. Are unable/unwilling to abstain from drugs and alcohol for 24 hours prior to the study

发起方

niversity College London