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Clinical Trials/NCT05765552
NCT05765552
Completed
Not Applicable

Effects Of Dual-Task Training On Balance, Fear Of Falling,Cognitive Functions, Dual-Task Performance, Depression And Quality Of Life In Individuals With Alzheimer

Ege University1 site in 1 country34 target enrollmentApril 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alzheimer Disease
Sponsor
Ege University
Enrollment
34
Locations
1
Primary Endpoint
Timed Up And Go(TUG)
Status
Completed
Last Updated
5 months ago

Overview

Brief Summary

The purpose of this study is to investigate the effects of dual-task training on balance, fear of falling, cognitive functions, dual-task performance, depression and quality of life in individuals with Alzheimer.

Detailed Description

Eligible participants will be randomized to control or dual-task training group.Control group will receive conventional therapy generally consisted of lower and upper range of motion exercises for 30 minutes 2 times a week for 8 weeks.Dual-task training group will receive exercises involving motor-cognitive dual-task exercises for 30 minutes 2 times a week for 8 weeks.Each participant will be assessed before and after the 8 weeks of treatment.

Registry
clinicaltrials.gov
Start Date
April 15, 2023
End Date
April 15, 2024
Last Updated
5 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mehmet Ozkeskin

Asisstant Professor

Ege University

Eligibility Criteria

Inclusion Criteria

  • having been diagnosed with mild or moderate Alzheimer's disease
  • able to walk with or without assistance
  • having sufficient visual and auditory ability to perform the cognitive tests
  • being fit to perform physical exercises
  • being able to participate in proposed interventions and assessments

Exclusion Criteria

  • having a neurological disorder other than Alzheimer
  • having any musculoskeletal problems that can affect balance
  • having any contraindication to exercise
  • functional limitation or sensory impairment that may affect performance
  • major depression

Outcomes

Primary Outcomes

Timed Up And Go(TUG)

Time Frame: eight weeks

It is a frequently used test that evaluates functional mobility and dynamic balance. At the beginning of the test, individuals sit in a chair. A distance of 3 m is set in front of the patient. With the start command, the patient gets up from his seat and walks 3 m, turns around and walks back and sits. With the start command, the time until the moment of sitting on the chair is recorded in seconds.Shorter duration indicates better functional mobility.

5 Times Sit To Stand Test(5XSST)

Time Frame: eight weeks

5XSST evaluates lower extremity functional strength, transitional movements, balance and fall risk. The time it takes for the participant to sit and get up from a chair 5 times is recorded in seconds. Interpretations are made about balance and fall risk by comparing the norm times for age with the time the individual completes the test.

Cognitive Reserve Index Questionaire(CRIq)

Time Frame: eight weeks

CRIq assesses an individual's cognitive reserve through compiling information about their entire adult life. If the participant has a suspected or confirmed cognitive weakness, the questionnaire must be answered by a family member or caregiver. The total score is obtained by recording the frequency of the individual's educational life, work and leisure activities in years. According to the score, the participant's cognitive reserve is interpreted as low, low - medium, medium, medium - high or high

Quality of Life in Alzheimer's Disease(QOL-AD)

Time Frame: eight weeks

There are two versions of the scale: patient and family member/caregiver. In order to maximize construct validity, the scale is filled in independently by both patients and caregivers. It consists of questions asked about different aspects of life in order to determine the quality of life of the person. For each question, they are asked to choose the most appropriate one from the Poor, Fair, Good or Excellent answers.Higher scores indicate better quality of life.

Geriatric Depression Scale(GDS)

Time Frame: eight weeks

The scale consists of 30 questions questioning how the participant felt in the past week. The person is asked to give the appropriate Yes(0) or No(1) answer to each question.Scores higher than 5 indicate depression.

Secondary Outcomes

  • Mini Mental Test(MMT)(eight weeks)
  • Modified Falling Efficacy Scale(MFES)(eight weeks)
  • Dual-Task Questionnaire(DTQ)(eight weeks)

Study Sites (1)

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