Effect of Whole Body Vibration Training on Two Different Devices on Osteoporotic Risk Factors in Postmenopausal Women. A Randomized Controlled Trial.
Overview
- Phase
- Phase 3
- Status
- Terminated
- Sponsor
- University of Erlangen-Nürnberg Medical School
- Enrollment
- 108
- Locations
- 1
- Primary Endpoint
- Bone Mineral Density
Overview
Brief Summary
There is general agreement that physical exercise can positively influence osteoporotic fracture risk along two pathways: first by reducing the risk of falls via an improvement of fall related neuromuscular abilities; second by increasing bone strength.
Whole body vibration (WBV) training has recently been proposed as a new approach for prevention and treatment of osteoporosis. Animal studies have shown evidence that WBV may be an effective method to improve bone mass, architecture and strength. However, the results of human WBV training studies are rather heterogeneous.
In the Erlangen Longitudinal Vibration Study II (ELVIS II), a randomized, controlled 12 month lasting study the investigators determine the effect of a thrice weekly WBV training on two different devices on the osteoporotic risk factors: bone mineral density, falls and neuromuscular performance. Particular the investigators compare a bipedal vertical oscillating Plate with a plate which rotates around a central axis leading to a side-alternating loaning.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 60 Years to 75 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •females 60 - 75 years old
- •caucasian race
Exclusion Criteria
- •CHD-diseases
- •thrombosis, embolism
- •fractures at lumbar spine or hip
- •secondary osteoporosis
- •hyperparathyroidism
- •medication, diseases with impact on muscle or bone
- •hip or knee implant
Outcomes
Primary Outcomes
Bone Mineral Density
Time Frame: Baseline, 12 months
Secondary Outcomes
- Quality of life(baseline, 12 month)
- falls(daily over 12 month)
- muscle strength(baseline, 12 months)
Investigators
Wolfgang Kemmler
Principal Investigator
University of Erlangen-Nürnberg Medical School