Effect of Whole Body Vibration Training on Two Different Devices on Osteoporotic Risk Factors in Postmenopausal Women. A Randomized Controlled Trial.
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 发起方
- 入组人数
- 108
- 试验地点
- 2
- 主要终点
- Bone Mineral Density
研究概览
简要总结
There is general agreement that physical exercise can positively influence osteoporotic fracture risk along two pathways: first by reducing the risk of falls via an improvement of fall related neuromuscular abilities; second by increasing bone strength.
Whole body vibration (WBV) training has recently been proposed as a new approach for prevention and treatment of osteoporosis. Animal studies have shown evidence that WBV may be an effective method to improve bone mass, architecture and strength. However, the results of human WBV training studies are rather heterogeneous.
In the Erlangen Longitudinal Vibration Study II (ELVIS II), a randomized, controlled 12 month lasting study the investigators determine the effect of a thrice weekly WBV training on two different devices on the osteoporotic risk factors: bone mineral density, falls and neuromuscular performance. Particular the investigators compare a bipedal vertical oscillating Plate with a plate which rotates around a central axis leading to a side-alternating loaning.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •females 60 - 75 years old
- •caucasian race
排除标准
- •CHD-diseases
- •thrombosis, embolism
- •fractures at lumbar spine or hip
- •secondary osteoporosis
- •hyperparathyroidism
- •medication, diseases with impact on muscle or bone
- •hip or knee implant
结局指标
主要结局
Bone Mineral Density
时间窗: Baseline, 12 months
次要结局
- Quality of life(baseline, 12 month)
- falls(daily over 12 month)
- muscle strength(baseline, 12 months)
研究者
Wolfgang Kemmler
Principal Investigator
University of Erlangen-Nürnberg Medical School