Evaluation of propofol target-controlled infusion (TCI) anaesthesia in infants aged 6 months to 3 years

Completed

• Conditions: Intravenous general anaesthesia in infants and young children; Surgery

• Registration Number: ISRCTN00098907
• Lead Sponsor: niversity of Glasgow (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-08-29
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Healthy male and female children aged 6 months - 3 years (inclusive)
2. Weight 7-16 kg
3. Elective surgery of expected duration >=30 minutes
4. American Society of Anaesthesiologists (ASA) Grade 1 or 2
5. Written informed consent from parent
6. Child suitable for intravenous induction and maintenance of anaesthesia with propofol
7. Children with no contraindication to application of local anaesthetic cream or gel to the cannulation site for intravenous induction

Exclusion Criteria

1. Age <6 months or >3 years (>36 months)
2. Weight <7 kg or >=17 kg
3. Children undergoing urgent or emergency surgical procedures
4. Expected duration of surgery <30 minutes
5. ASA Grade 3-5
6. No written informed consent from parent
7. Children with difficult venous access
8. Children who need or wish inhalational induction
9. Children who will need intermittent positive pressure ventilation along with the use of muscle relaxant
10. Patients who need sedative premedication
11. Propofol contraindicated (allergy to propofol or its formula components)
12. Local anaesthetic cream or gel contraindicated

Study & Design

• Study Type: Interventional
• Study Design: Not specified