TARGET-CONTROLLED INFUSION OF PROPOFOL-FENTANYL VERSUS DESFLURANE ON HEPATOCELLULAR INTEGRITY IN CIRRHOTIC PATIENTS UNDERGOING MAJOR HEPATIC RESECTIO

Not Applicable

• Conditions: Digestive System; Surgery; Hepatocellular carcinoma; Anaesthesia

• Registration Number: PACTR201402000759256
• Lead Sponsor: Amr el safty

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-02-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult patient.
Cirrhotic patient.
Child A classified patient.

Exclusion Criteria

- history of esophageal disease.
- Patients undergoing re-operation.
- history of allergic reactions to drugs.
- recent anaesthetia (within the previous 7 days).
- Patients who bled profusely during their operation, who are haemodynamically unstable, or who need inotropic support.
- preoperative renal dysfunction

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
iver function test [glutathione S transferase];Kidney function test [microalbumin in urine]

Secondary Outcome Measures

Name	Time	Method
Hemodynamic parameters[corrected flow time,stroke volume,systemic vascular resistance