Acupuncture combined with ondansetron for prevention of postoperative nausea and vomiting in gynaecological patients undergoing laparoscopic surgery: a randomized controlled trial
- Conditions
- Postoperative nausea and vomiting
- Registration Number
- ITMCTR2100004305
- Lead Sponsor
- Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- Not specified
1. Women aged 18-65 years;
2. Subjects with ASA grade I or II;
3. Patients scheduled for gynecological laparoscopic ovarian or uterine surgery under general anesthesia;
4. Patients who are expected to use opioids after operation;
5. Subjects whose estimated operation time (from anesthesia induction to wound closure) >= 1H;
6. Subjects who voluntarily participated in the trial and signed informed consent.
1. Pregnant, lactating or menstrual women and smoking women;
2. Patients scheduled for laparoscopic surgery for gynecological malignancies;
3. Patients with nausea, vomiting or both within 24 hours before operation;
4. Patients who received antiemetic drugs, opioids or glucocorticoids within 24 hours before operation;
5. Patients with severe hepatic and renal insufficiency, central nervous system injury, vertebrobasilar insufficiency, vestibular diseases, coagulation disorders or other blood diseases;
6. Patients with skin damage at acupuncture point or eczema and other skin diseases;
7. Subjects who participated in other studies in recent 3 months;
8. Patients known to be allergic to ondansetron or metoclopramide.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the incidence of PONV in the first 24 hours postoperative;
- Secondary Outcome Measures
Name Time Method the incidence of PON, the incidence of POV and the incidence of PONV in other evaluation periods;rescue antiemetic need;assessment of satisfaction score;episodes of vomiting;pain intensity;credibility and expectancy;degree of nausea;Time to first flatus;assessment of total postoperative analgesics dosage;