administration of Ondansetron before spinal anaesthesia for prevention of hypotension in elective caesarean section.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/02/031305
- Lead Sponsor
- Vijayanagar institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Primiparous and multiparous parturient women with a single foetus posted for Elective caesarean section
2)37â??42 weeks of gestation
3)ASA grade II
4)Normal foetal profile
Exclusion Criteria
1)Contraindication for or refusal of spinal anaesthesia
2)Hypertension (SBP >140 mm Hg or DBP >90 mm Hg), Chronic or gestational hypertension or preeclampsia
3)Cardiovascular and/or cerebrovascular diseases
4)Diabetes mellitus
5)Administration of 5-hydroxytryptamine (5-HT3) reuptake inhibitors or drugs for the treatment of migraines
6)Treatment with antiemetics (including 5 HT3 blockers) within 72 h of surgery
7)Hypersensitivity to ondansetron, fentanyl, or bupivacaine
8)Obesity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of hypotensionTimepoint: after spinal anaesthesia throughout the procedure.
- Secondary Outcome Measures
Name Time Method 1)Need of vasopressors <br/ ><br> 2)intraoperative nausea and vomiting (INOV) <br/ ><br>3)neonatal outcomes in terms of APGAR score <br/ ><br>Timepoint: after spinal anaesthesia throughout the procedure