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Clinical Trials/NCT05511311
NCT05511311
Unknown
N/A

Development of Frailty Prevention Clinic in Geriatric Comprehensive Clinic RSCM: The Role of Resistance Training as Sarcopenia and Frailty Management Towards Frailty Score, Sarcopenia Score, and Quality of Life

Indonesia University1 site in 1 country220 target enrollmentJanuary 1, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Frailty
Sponsor
Indonesia University
Enrollment
220
Locations
1
Primary Endpoint
Frailty Status
Last Updated
3 years ago

Overview

Brief Summary

There is an increasing number of elderly population, not only in Indonesia, but also in the world. With increasing of age, there is also an increasing number of elderly with sarcopenia and frailty. Both of the diseases can lead to dependency, decrease quality of life, and morbidity. Besides nutrition, physical activity, especially resistance training is proven to be beneficial in improving sarcopenia and frailty condition.

Currently in Cipto Mangunkusumo National Hospital (RSCM), there is no comprehensive frailty prevention clinic in the geriatric inpatient clinics. This research can be the base of frailty and sarcopenia treatment in RSCM.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
November 30, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Siti Setiati

Prof

Indonesia University

Eligibility Criteria

Inclusion Criteria

  • Patients 60 years old or orlder
  • Categorized as Pre-frail or Frail based on FRAIL criteria
  • Is not in routine physical activity in the past 3 months
  • Succeeded Mini Physical Performance Test with score 11 or more

Exclusion Criteria

  • Cognitive Disturbance (Abbreviated Mental Test \< 8)
  • Not consenting to join the trial

Outcomes

Primary Outcomes

Frailty Status

Time Frame: 12 weeks

The FRAIL scale includes 5 components: Fatigue, Resistance, Ambulation, Illness, and Loss of weight (10). Frail scale scores range from 0-5 (i.e., 1 point for each component; 0=best to 5=worst) and represent frail (3-5), pre-frail (1-2), and robust (0) health status

Sarcopenia Status

Time Frame: 12 weeks

Measured using: * BIA: \<7.0 kg/m2 in men and \<5.7 kg/m2 in women * Five times sit to stand: ≥12 seconds * Hand-grip strength: \<28 kg for men and \<18 kg for women

Walking Speed

Time Frame: 12 weeks

\<1.0 m/s

Patient's Quality of Life

Time Frame: 12 weeks

Measured by EQ-5D: ranging from 0 ('worst imaginable health') to 100 ('best imaginable health')

Secondary Outcomes

  • Prevalence of Frailty(12 weeks)
  • Prevalence of Sarcopenia(12 weeks)

Study Sites (1)

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