comparison effects of two regimens: prednisolone plus cimetidine versus prednisolone plus colchicine in control of frequency and duration of fever episodes In the Periodic fever, Aphthous stomatitis, Pharyngitis and Adenitis in children referred to pediatric medical center
Phase 2
Recruiting
- Conditions
- PFAPA syndrome.
- Registration Number
- IRCT20191222045847N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
1. Age of onset of symptoms from 1 year to 10 years of age 2. Absence of inflammatory or other rheumatic disease at the same time 3.there are No concomitant disease that this drugs contraindicated on it (prednisolone, cimetidine, colchicine).
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency and duration of fever episodes in PFAPA. Timepoint: Before starting the study and 3 months later. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method