Lung Ultrasound and Alveolar Recruitment in Mechanically Ventilated Infants

Not Applicable

Completed

• Conditions: Pulmonary Atelectasis
• Interventions: Device: Lung ultrasound

• Registration Number: NCT02584023
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Investigators hypothesized that lung ultrasound-assisted recruitment maneuver would be beneficial in mechanically ventilated infants compared to those who did not receive lung ultrasound and alveolar recruitment maneuver.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2015-10-20
• Study First Submitted QC: 2015-10-21
• Study First Posted: 2015-10-22
• Primary Completion: 2016-01
• Study Completion: 2016-01
• Status Verified: 2016-06
• Last Update Submitted: 2016-06-21
• Last Update Posted: 2016-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Minor surgery less than 2 hours under general anesthesia
• Mechanically ventilated after endotracheal intubation

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Exclusion Criteria

• History of surgery on the lungs
• Laparoscopic surgery
• Abnormal preoperative chest radiograph findings including atelectasis, pneumothorax, pleural effusion, and pneumonia
• Considered inappropriate by the investigator

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Alveolar recruitment	Lung ultrasound	Perform lung ultrasound twice during the perioperative period after the endotracheal intubation and and at the end of surgery. Conduct alveolar recruitment maneuver after first lung ultrasound assessment.
Control	Lung ultrasound	No intervention during the perioperative period. Perform lung ultrasound twice only for the diagnostic purpose after the endotracheal intubation and and at the end of surgery.

Primary Outcome Measures

Name	Time	Method
Postoperative incidence of pulmonary atelectasis	within the first day after the surgery

Secondary Outcome Measures

Name	Time	Method
Intraoperative incidence of pulmonary atelectasis after endotracheal intubation	from the moment of endotracheal intubation until the end of surgery, up to 6 hours
Intraoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value)	from the induction of general anesthesia until the end of the surgery, up to 6 hours
Postoperative incidence of pulse oximetry (SpO2) ≤ 95% (or 10% below the baseline value)	within the first day after the surgery

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of