Registry of Emergent Large veSsel oCclUsion duE to IntraCranial AtherosclerosiS

Active, not recruiting

• Conditions: Mechanical Thrombectomy; Large Vessel Occlusion; Intracranial Stenosis
• Interventions: Other: No Intervention

• Registration Number: NCT05403593
• Lead Sponsor: Medical University of South Carolina

Brief Summary

The aim of this study is to develop an international multicenter registry of patient data and outcomes for patients undergoing mechanical thrombectomy for emergent large vessel occlusion with residual underlying stenosis following successful revascularization.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-15
• Study First Submitted: 2022-05-24
• Study First Submitted QC: 2022-05-31
• Study First Posted: 2022-06-03
• Status Verified: 2024-03
• Primary Completion: 2024-03-05
• Last Update Submitted: 2024-03-05
• Last Update Posted: 2024-03-07
• Study Completion: 2024-06-14

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

• All patients undergoing mechanical thrombectomy
• AND have intracranial stenosis
• Patients aged 18-90 years

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Participants with Intracranial Stenosis	No Intervention	Patients with Intracranial Stenosis who undergo Mechanical Thrombectomy will be added to the registry given they meet the age inclusion criteria.

Primary Outcome Measures

Name	Time	Method
modified Rankin score	3 months	standard stroke score measuring disability level delivered by physician with level 0-6 with 0 being no symptoms and 6 being death. Outcome measured by the distribution of mRS score.
Mortality	90 day	Death at 90 days post intervention

Trial Locations

Locations (19)

Nova University Lisbon; 🇵🇹 LIsbon, Portugal

Univeristy of Chicago Medicine; 🇺🇸 Chicago, Illinois, United States

Advocate Aurora Health; 🇺🇸 Oak Lawn, Illinois, United States

Indiana Health Univeristy Hospital; 🇺🇸 Indianapolis, Indiana, United States

Thomas Jefferson University Hospital; 🇺🇸 Philadelphia, Pennsylvania, United States

Univeristy of Iowa Hospital; 🇺🇸 Iowa City, Iowa, United States

Univeristy of Miami Health System; 🇺🇸 Miami, Florida, United States

Emory Univeristy Hospital; 🇺🇸 Atlanta, Georgia, United States

Imam Abdulrahman Alfaisal University; 🇸🇦 Dammam, Saudi Arabia

Massachuestts General Hospital; 🇺🇸 Boston, Massachusetts, United States

Brown University; 🇺🇸 Providence, Rhode Island, United States

The University of Tennessee Health Science Center; 🇺🇸 Memphis, Tennessee, United States

Universitätsmedizin Göttingen; 🇩🇪 Göttingen, Germany

Univeristy of Texas Health Science Center at San Antonio; 🇺🇸 San Antonio, Texas, United States

Yale New Haven Hospital; 🇺🇸 New Haven, Connecticut, United States

Atrium Health Wake Forest Baptist; 🇺🇸 Winston-Salem, North Carolina, United States

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States

Careggi Universtiy Hospital; 🇮🇹 Florence, Italy

Universitätsspital Basel; 🇨🇭 Basel, Switzerland