IVTCC 2.0: a Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry
- Conditions
- CardiomyopathyVentricular TachycardiaPremature Ventricular Contraction (PVC)Ventricular Arrhythmia
- Registration Number
- NCT04520347
- Lead Sponsor
- University of California, Los Angeles
- Brief Summary
This is a prospective multi-center international registry. The objective of this registry is to collect prospective data on patients undergoing catheter ablation for Ventricular Tachycardia (VT) and Premature Ventricular Contractions (PVC). The registry will be used for clinical monitoring, research, and quality improvement purposes.
- Detailed Description
Sudden cardiac death (SCD), predominantly due to ventricular tachyarrhythmias, is a leading cause of mortality in the United States and around the world. Catheter ablation of ventricular arrhythmias has proven efficacious in reducing the burden of arrhythmias and reducing implantable cardiac defibrillator (ICD) shocks.
The aim of this study is to create a prospective international database registry that will allow for better assessment of the outcomes of catheter ablation of ventricular arrhythmias. The registry, with approximately 30 participating centers, will help to identify the overall success rates and associated benefits of the procedure and provide more comprehensive data on understudied populations and treatment.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 10000
- All patients undergoing catheter ablation for ventricular tachycardia (VT) or premature ventricular contractions (PVCs).
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ventricular tachycardia (VT) recurrence From date of procedure assessed by shock, Anti-Tachycardia Pacing, or repeat procedure, up to 10 years. Freedom from ventricular tachycardia episodes requiring ICD Intervention (shock or Anti-Tachycardia Pacing) or repeat procedure.
- Secondary Outcome Measures
Name Time Method Rate of complications From date of procedure assessed up to 12 months. Cardiovascular-related and procedure-related major complications and/or adverse events.
Time to transplant or death From date of procedure assessed by date of transplant and/or death, up to 10 years.
Trial Locations
- Locations (40)
Columbia University Irving Medical Center
🇺🇸New York, New York, United States
Wellspan Health
🇺🇸York, Pennsylvania, United States
Banner Health, University of Arizona Medical Center
🇺🇸Phoenix, Arizona, United States
Cedars-Sinai Medical Center
🇺🇸Los Angeles, California, United States
University of California, Los Angeles
🇺🇸Los Angeles, California, United States
University of California, Davis
🇺🇸Sacramento, California, United States
University of California San Francisco
🇺🇸San Francisco, California, United States
University of Colorado Hospital
🇺🇸Aurora, Colorado, United States
Hartford HealthCare
🇺🇸Hartford, Connecticut, United States
University of Florida Health
🇺🇸Gainesville, Florida, United States
The Kansas City Heart Rhythm Institute
🇺🇸Kansas City, Kansas, United States
University of Maryland Medical Center
🇺🇸Baltimore, Maryland, United States
Johns Hopkins Heart and Vascular Institute
🇺🇸Baltimore, Maryland, United States
Boston Children's Hospital
🇺🇸Boston, Massachusetts, United States
Brigham and Women's Hospital
🇺🇸Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
🇺🇸Boston, Massachusetts, United States
UMass Memorial Health Care
🇺🇸Worcester, Massachusetts, United States
University of Michigan Frankel Cardiovascular Center
🇺🇸Ann Arbor, Michigan, United States
University of Minnesota VA Medical Center
🇺🇸Minneapolis, Minnesota, United States
Mayo Clinic
🇺🇸Rochester, Minnesota, United States
Washington University in St. Louis
🇺🇸Saint Louis, Missouri, United States
Montefiore Medical Center
🇺🇸Bronx, New York, United States
The Mount Sinai Hospital
🇺🇸New York, New York, United States
Oregon Health & Science University
🇺🇸Portland, Oregon, United States
Children's Hospital of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States
University of Pennsylvania Health System
🇺🇸Philadelphia, Pennsylvania, United States
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States
Vanderbilt Heart and Vascular Institute
🇺🇸Nashville, Tennessee, United States
Texas Cardiac Arrhythmia Institute at St. David's Medical Center
🇺🇸Austin, Texas, United States
Houston Methodist Hospital
🇺🇸Houston, Texas, United States
University of Utah Health
🇺🇸Salt Lake City, Utah, United States
University of Virginia Health System
🇺🇸Charlottesville, Virginia, United States
University of Washington Medical Center
🇺🇸Seattle, Washington, United States
The Montreal Heart Institute
🇨🇦Montréal, Canada
Shaare Zedek Medical Center
🇮🇱Jerusalem, Israel
Dokkyo Medical University Koshigaya Hospital
🇯🇵Koshigaya, Japan
Leiden University
🇳🇱Leiden, Netherlands
Erasmus Medical Center
🇳🇱Rotterdam, Netherlands
Gregorio Marañón General University Hospital
🇪🇸Madrid, Spain
St. George's Hospital
🇬🇧Wandsworth, United Kingdom