Patent Foramen Ovale in Children With Migraine Headaches
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 109
- 试验地点
- 1
- 主要终点
- The prevalence of PFO in children with migraine headaches
研究概览
简要总结
This study will be the first to provide data about the relationship between PFO and migraine in children. By establishing the actual prevalence, we will better understand if PFO plays a role in the occurence of pediatric migraine and, thus, provide the incentive to perform additional studies evaluating whether PFO closure is an effective treatment option for pediatric migraine. For children with migraine headaches, discovering novel and effective treatments would be life altering.
详细描述
Specific Aim 1 Using contrast transthoracic echocardiography, compare the prevalence of a PFO in children with migraine headache with the established incidence of PFO published for the general population.
Specific Aim 2 Using contrast transcranial Doppler, examine the relationship between the degree of right to left atrial shunting with the presence or absence of aura in children with migraine.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Years 至 17 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Greater than or equal to six years of age and less than 18 years of age.
- •Diagnosis of migraine headache based on the International Headache Society Criteria.
- •English speaking patients (and parent/guardians where appropriate).
- •Signed informed consent/assent (as appropriate) given by patient, parent or legal guardian.
排除标准
- •Inability to cooperate with imaging studies.
- •Known congenital heart disease.
- •Parent or guardian is unwilling to have their child undergo contrast echocardiography.
结局指标
主要结局
The prevalence of PFO in children with migraine headaches
时间窗: One year
次要结局
未报告次要终点