High chloride level, anaemia and severity of COVID-19

Not Applicable

• Conditions: Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhereHealth Condition 2: J128- Other viral pneumonia

• Registration Number: CTRI/2020/11/029060
• Lead Sponsor: Vedaghosh Amara

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients aged 18-80 years admitted to critical care unit and on oxygen support with either invasive ventilation/Non- invasive ventilation ( NIV) / high flow nasal cannula (HFNC) /non rebreathing mask (NRBM) /venturi devices as deemed suitable by ICU consultant

Exclusion Criteria

No evidence of bleeding in any

Patients with preexisting disorders causing hyperchloraemia like severe diarrhea

Chronic or acute kidney disease (GFR <15mL/min)

Any patient on dialysis.

Extremely high ingestion of salt water and high ingestion of dietary salt.

Use of drugs like carbonic anhydrase inhibitors

Confounding factors of raised CRP like burns, trauma, tuberculosis, myocardial infarction, chronic inflammatory disorders like lupus, vasculitis or rheumatoid arthritis, inflammatory bowel disease and certain cancers.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Chloride level,CRP,Ferritin ,Haemoglobin.Timepoint: Day 3 of ICU admission.

Secondary Outcome Measures

Name	Time	Method
Development of Acute Kidney Injury <br/ ><br>Outcome of ICU stay. <br/ ><br> <br/ ><br>Timepoint: 28 days after ICU admission.