Comparison of the effects of cilnidipine and benidipine on urinary excretions of albumin and type-IV collagen in Japanese hypertensive type-2 diabetic patients with nephropathy.
Not Applicable
Completed
- Conditions
- hypertensive type-2 diabetic patients with nephropathy
- Registration Number
- JPRN-UMIN000005384
- Lead Sponsor
- Akita University Garduate School of Medicine, Department of Endocrinology, Diabetes and Geriatric Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
acute illness or malignant tumors drug allergy with pregnant or breast feeding, or candidates with such situations patients who are judged as inappropriate for inclusion by their physicians
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in urinary excretions of albumin and type-IV collagen between groups with either cilnidipine or benidipine
- Secondary Outcome Measures
Name Time Method Changes in blood pressure and glycemic control
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms differentiate cilnidipine and benidipine in reducing albuminuria in diabetic nephropathy?
How does cilnidipine compare to benidipine in inhibiting type-IV collagen excretion for hypertensive type-2 diabetic nephropathy patients?
Which biomarkers correlate with response to dihydropyridine calcium channel blockers in Japanese diabetic nephropathy populations?
What adverse event profiles distinguish cilnidipine from benidipine in managing hypertension and diabetic kidney disease?
Are there combination therapies with cilnidipine or benidipine that enhance renal protection in type-2 diabetes with nephropathy?