Combined Cognitive-Behavioral and Pharmacological Continuation and Maintenance Treatment of Recurrent Depressio

Completed

• Conditions: Recurrent depression; Mental and Behavioural Disorders; Depression

• Registration Number: ISRCTN81212636
• Lead Sponsor: niversity of Jena (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-05-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 168

Inclusion Criteria

1. Diagnosis of recurrent depressive disorder (>3 major depressive episodes [MDE]), currently in remission (ICD-10 F33.4)
2. Complete remission over 8 weeks after acute treatment of MDE
3. At least one index depressive episode within 12 months prior to the treatment
4. Hamilton Rating Scale for Depression (HRSD-17) score of 9 or less over 8 weeks prior to treatment
5. Age 18-70 years

Exclusion Criteria

1. Organic mental disorder
2. Psychological or behavioral disorders caused by psychotropic substances
3. Schizophrenia, schizoaffective disorder
4. Bipolar depression
5. Adjustment disorders
6. Borderline personality disorder
7. Mental retardation
8. Acute suicidality
9. Severe co-morbid medical condition
10. More than five individual sessions of regular cognitive-behavioral treatment within one year before randomization

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to first relapse

Secondary Outcome Measures

Name	Time	Method
Depression (Hamilton Rating Scale for Depression)