Effects of Inspiratory and Respiratory Pressure Threshold Training in Patients With Chronic Obstructive Pulmonary Disease
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- respiratory muscle strength measurements
研究概览
简要总结
The study will investigate the effects of different training types ,including combined inspiratory with expiratory pressure threshold training,inspiratory pressure threshold training on patients with chronic obstructive airway disease and investigate whether expiratory pressure threshold training associated with inspiratory pressure threshold training would be better than inspiratory pressure threshold training alone, with regard to exercise capacity, respiratory muscle strength and endurance.
详细描述
We will study 60 patients diagnosed of chronic obstructive pulmonary disease.The monitoring will be done for 8 weeks. Pressure-threshold respiratory trainers were calibrated to provide different loads according to the patients against inspiration (IMST) or expiration (EMST). Those chronic obstructive pulmonary disease clinically stable patients stratified from mild to very severe GOLD stages, were blinded to randomly divided into 3 different groups: a)control group:without any training;b) inspiratory and expiratory pressure threshold training group: trained with the pressure threshold trainer twice time daily with 15minutes' duration;c)inspiratory pressure threshold training group:trained with the pressure threshold trainer twice time daily with 15 minutes' duration,different from the b group,the expiratory pressure threshold is calibrated at 0.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically stable COPD with diagnosis of forced expiratory volume at one second(FEV1)/forced vital capacity(FVC) < 70%
排除标准
- •Cancer Unstable heart disease Neuromusculoskeletal disorder mental disorder Active smokers
研究组 & 干预措施
control group
without inspiratory and expiratory pressure threshold training
inspiratory pressure training group
The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.
干预措施: inspiratory pressure training group (Device)
mixed training group
The patients will perform daily in 2 sessions of 30 minutes, using a pressure threshold trainer.
干预措施: mixed training group (Device)
结局指标
主要结局
respiratory muscle strength measurements
时间窗: baseline and 8 weeks
次要结局
- 6-minute walking test(baseline and 12 weeks)
- perceived exertion for leg fatigue (Borg-scale)(baseline and 8 weeks)
- respiratory muscle endurance text(baseline and 8 weeks)
- modified british medical research council(mMRC) questionnaire(baseline and 8 weeks)