The Effects of Inspiratory Pressures on Diaphragmatic Contraction in People After Stroke

Completed

• Conditions: Stroke

• Registration Number: NCT06267768
• Lead Sponsor: Hong Kong Metropolitan University

Brief Summary

This is a cross-sectional study to determine the optimal inspiratory muscle training (IMT) intensity for stroke survivors. Participants will breathe through a pressure threshold inspiratory loading device with varying loads in random order. Each IMT intensity protocol consists of 10 breaths. During the test, accessory inspiratory muscle activity will be measured with surface electromyography (sEMG) and diaphragm thickness will be used to assessed with ultrasonography. Repeated-measures ANOVA will be used for statistical analysis to determine the most effective training intensity for future study.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-02-04
• Study First Submitted QC: 2024-02-15
• Study First Posted: 2024-02-20
• Study Start: 2024-03-02
• Primary Completion: 2024-08-17
• Study Completion: 2024-08-17
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-27
• Last Update Posted: 2025-01-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diaphragmatic thickening fraction	Data will be measured at baseline and at the end of each inspiratory muscle training intensity protocol;	Diaphragmatic thickening fraction is determined by "(thickness of the diaphragm at end inspiratory - thickness at end expiratory)/thickness at end expiratory". Diaphragmatic thickness will be measured by ultrasonography.

Secondary Outcome Measures

Name	Time	Method
Perceived Exertion Borg scale	Data will be measured at the end of each inspiratory muscle training intensity protocol;	This is a vertical scale quantified from 0 to 10, where 0 represents no symptoms, and 10 represents the maximum symptoms. The Borg score provides an individual measurement of the exercise intensity.
Muscle activation of the sternocleidomastoid muscle	Data will be measured at baseline and at the end of each inspiratory muscle training intensity protocol;	Surface electromyography will be used to measure accessory inspiratory muscle (sternocleidomastoid muscles) activity during each inspiratory muscle training intensity protocol.

Trial Locations

Locations (1)

Shenzhen Second People's Hospital; 🇨🇳 Shenzhen, None Selected, China