ACTRN12617000400369招募中未知
Effect of Progressive Resistance Training on insulin resistance and depression in adults with Metabolic Syndrome and Major Depressive Disorder.
Dr Yorgi Mavros0 个研究点目标入组 44 人开始时间: 2017年3月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 44
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 40 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Major Depressive Disorder according to DSM 5 criteria,
- •*If not receiving any treatment; PHQ-9 of 10 or higher (moderate depression)
- •*If receiving treatment, PHQ-9 of 5 or higher (mild depression)
- •2. Metabolic syndrome according to IDF criteria
- •*Central obesity (Waist circumference Men; greater than or equal to 94 cm men. Women; greater than or equal to 80 cm) and any 2 of the following:
- •*Raised triglycerides (150 mg/dL (1.7 mmol/L) or higher, or specific treatment for this lipid abnormality)
- •*Low HDL cholesterol (Less than 40 mg/dL (1.03 mmol/L) in men and less than 50 mg/dL (1.29 mmol/L) in women or specific treatment for this lipid abnormality
- •*Hypertension (systolic BP of 130 or higher, or diastolic BP of 85 mm Hg or higher, or treatment of previously diagnosed hypertension)
- •*High fasting plasma glucose ((FPG) of 100 mg/dL (5.6 mmol/L) or higher.
- •3. at least 40 years of age
- •4. Not on oral hypoglycaemics or insulin therapy
- •5. No diagnosis of type 2 diabetes, or not found to have type 2 diabetes during the screening process
- •6. Sedentary - less than 150 minutes per week of structured moderate or vigorous physical activity.
- •7. No terminal or rapidly progressing illness, or condition that precludes participation in progressive resistance training
排除标准
- •Type 2 diabetes or use of oral hypoglycaemic medication or insulin
- •Suicide ideation
- •Illegal drug use
- •Alcohol dependence/abuse (3 or 4 on CAGE questionnaire)
- •Substance abuse disorder
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