Effect of Progressive Resistance Training on Gut Microbiota and Inflammation in Adults with Crohn’s Disease & Ulcerative Colitis: A Randomized Controlled Trial.

The University of Sydney0 sites90 target enrollmentFebruary 5, 2018

Overview

No summary available.

Registry

who.int

Start Date

February 5, 2018

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

•1\. Ulcerative Colitis (UC) or Crohn’s Disease (CD) of 3 months or greater duration.
•2\. Inactive to moderately active disease state based on scores from the Total Mayo Scoring Index for UC (scores of 0 to 10\) and Crohn’s Disease Activity Index (CDAI) for CD (scores of 0 to 450\). This change was made prior to any enrolments.

•1\.Absolute contraindications to exercise testing and training as defined by the American College of Sports Medicine .
•2\.Planned major surgery within the first 3 months after randomisation.
•3\.Clinical evidence of any comorbid chronic disease that may interfere with the patient’s ability to enter the trial and undertake the testing and exercise intervention planned
•4\.Pregnant
•5\.Female planning pregnancy within the first 4 months after randomisation.
•6\.Participating in moderate aerobic training equal or greater than 150 minutes per week or vigorous aerobic training equal or greater than 75 minutes per week, or high intensity interval training
•7\.Those currently practicing resistance training, of any intensity equal or greater than one day per week
•8\.Participation in another clinical trial for which concurrent participation is deemed inappropriate
•Participants will be ineligible for the investigation of gut microbiota changes (therefore not required to give stool samples) if they have the following due to the influence on altering the gut microbiome:
•1\.Prior or concomitant/planned fecal microbiota transplantation or any rectal preparations for IBD currently