Frailty in Older HIV-infected Individuals
- Conditions
- HIV Infections
- Registration Number
- NCT03413683
- Lead Sponsor
- Chinese University of Hong Kong
- Brief Summary
Frailty has been proposed as a measure of biological (as opposed to chronological) aging. In this study the investigators plan to: (1) measure frailty in a cohort of older HIV-infected individuals in Hong Kong, and its association with mortality and quality of life; (2) identify risk factors predictive of development of frailty in HIV-infected individuals in Hong Kong; and (3) determine the outcomes of HIV-infected individuals in Hong Kong with and without frailty.
The following assessment will be done:
1. Physical examination including measuring height, weight, hip and waist circumference.
2. Grip strength, chair stand test, gait speed test, balance tests, and neurocognitive tests
3. Geriatric syndromes, screening for depression, disability and quality of life.
4. Blood tests during fasting state to measure metabolic parameters.
This is a prospective longitudinal observational study that lasts for 10 years.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 100
- HIV infection with positive anti-HIV antibody
- Age ≥50 years
- Refuses to consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frailty 10 years Frailty defined by frailty phenotype measurement, according to Fried (Fried et al., 2011) definition.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Prince of Wales Hospital
🇭🇰Sha Tin, Hong Kong