Effectiveness of Autologous Fibroblasts on Facial Rejuvenatio

Phase 4

Recruiting

• Conditions: patients who expressed dissatisfaction with their nasolabial folds and periorbital wrinkles based on a score of -1 or -2 on the SubjectWrinkle Assessment Scale; Nasolabial folds; Periorbital wrinkles

• Registration Number: TCTR20220527003
• Lead Sponsor: Research department, Faculty of Medicine Siriraj Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-27
• Study Completion: 2022-12-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

patients who expressed dissatisfaction with their nasolabial folds and periorbital wrinkles based on a score of -1 or -2 on the Subject
Wrinkle Assessment Scale

Exclusion Criteria

: (1) were pregnant or lactating; (2) had a history of connective tissue disorder, skin cancers, or related
diseases; (3) had previous autologous fibroblast treatment; (4) had previous treatment with fillers, lasers or
energy-based devices within the last 12 months; (5) had previous treatment using transdermal drug delivery,
chemical peeling or topical retinoid within the last month; or (6) had allergy to collagen, meat and dairy
products, gentamycin, amphotericin B, or related products.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
clinical improvement 1-, 3-, 6-, and 12-months follow-up increation of NLFs and POWs facial volume captured by Vectra H1 Imaging System

Secondary Outcome Measures

Name	Time	Method
safety 1-, 3-, 6-, and 12-months follow-up history taking and physical examination