Effectiveness of Autologous Fibroblasts on Facial Rejuvenatio
Phase 4
Recruiting
- Conditions
- patients who expressed dissatisfaction with their nasolabial folds and periorbital wrinkles based on a score of -1 or -2 on the SubjectWrinkle Assessment ScaleNasolabial foldsPeriorbital wrinkles
- Registration Number
- TCTR20220527003
- Lead Sponsor
- Research department, Faculty of Medicine Siriraj Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
patients who expressed dissatisfaction with their nasolabial folds and periorbital wrinkles based on a score of -1 or -2 on the Subject
Wrinkle Assessment Scale
Exclusion Criteria
: (1) were pregnant or lactating; (2) had a history of connective tissue disorder, skin cancers, or related
diseases; (3) had previous autologous fibroblast treatment; (4) had previous treatment with fillers, lasers or
energy-based devices within the last 12 months; (5) had previous treatment using transdermal drug delivery,
chemical peeling or topical retinoid within the last month; or (6) had allergy to collagen, meat and dairy
products, gentamycin, amphotericin B, or related products.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical improvement 1-, 3-, 6-, and 12-months follow-up increation of NLFs and POWs facial volume captured by Vectra H1 Imaging System
- Secondary Outcome Measures
Name Time Method safety 1-, 3-, 6-, and 12-months follow-up history taking and physical examination