CARBETOCIN COMPARED TO OXYTOCIN IN ACTIVE MANAGEMENT OF THIRD STAGE OF LABOUR IN AMINU KANO TEACHING HOSPITAL: A DOUBLE BLINDED RANDOMIZED CONTROLLED TRIA

Not Applicable

• Conditions: Postpartum Haemorrhage

• Registration Number: PACTR202205688707819
• Lead Sponsor: Faiza Lawan Mohammed

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-04-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 214

Inclusion Criteria

All pregnant women
•with singleton gestation
•at term
•at low risk of having PPH
•in early active phase of first stage of labour
who were to have spontaneous vaginal delivery

Exclusion Criteria

1.Pregnant women with medical disorders such as hepatic, cardiovascular, renal diseases, epilepsy, uncontrolled diabetes mellitus, sickle cell disease.
2.Gestational age <37 weeks.
3.Pregnant women with a previous caesarean scar, grandmultiparous women, multiple gestation, fetal macrosomia, previous PPH, anaemia, induction of labour, antepartum haemorrhage.
4.All pregnant women undergoing caesarean delivery.
5.Pregnant women in advanced labour and too distressed to provide informed consent.
6.Pregnant women in whom Oxytocin or Carbetocin are contraindicated: allergies to Oxytocin and its homologues.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of women with blood loss >/=500mls in each group

Secondary Outcome Measures

Name	Time	Method
Mean blood loss at delivery (in mls) in each group;Proportion of women receiving additional uterotonics;Proportion of women requiring additional surgical procedures (manual removal of placenta, uterine compression sutures, uterine or internal iliac artery ligation or hysterectomy);Proportion of women needing blood transfusion;Side effects of drugs;Cost effectiveness ratio