The Natural History of Parkinson's Disease-associated Spinal Disorders
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Natural history of spine disorders in idiopathic Parkinson's disease
研究概览
简要总结
This is a prospective single-institution longitudinal study to access quality of life and serial imaging and biodynamic testing to assess spinal disorders associated with Parkinson's disease patients.
详细描述
This is a prospective single-institution longitudinal study to access quality of life with PROMIS testing, ODI, NDI, VAS and short form 36 health physical component score. The study will also include serial radiographic assessments and biodynamic force plate and hand dynamometer testing. This study will follow for five years post-consent.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Idiopathic Parkinson Disease Early to mid-disease course (Hoehn and Yahr scale 1-3) Age 18-75
排除标准
- •Prior spinal fusion Diagnosis of ankylosing spondylitis, diffuse idiopathic spinal hyperostosis (DISH), or other systemic condition that affects spinal function Inability to consent Current incarceration Presence of other medical condition or neurologic condition that would hinder ability to perform biodynamic testing
结局指标
主要结局
Natural history of spine disorders in idiopathic Parkinson's disease
时间窗: Consent to five years
Natural history of spine disorders in idiopathic Parkinson's disease
次要结局
- Factors associated with the development and progression of Parkinson's related spinal disorders(consent to five years)
- Parameters for optimal management(consent to five years)
- Clinical impact of Parkinson's related spinal disorders(Consent to five years)
研究者
Andrew Grossbach
Associate Attending
Ohio State University