A comparative clinical study on mitrapanchak yoga and Avalgujbeejadi lepa in the management of Shwitra wsr to Vitiligo
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- will be evaluated
研究概览
简要总结
Shwitra is a disease described in Ayurveda; which is produced byvitiation of Vata, Pitta and Kapha Doshas. The signs and symptoms of Shwitra are; non exudative white, red orcoppery-red coloured patches on the skin, destruction of the skin lusture, lossand discolouration of the hair, roughness, dryness, itching and burningsensation of the patches. It can be correlated with Vitiligo which isprogressive whitening of the skin and hair characterized by the total absenceof melanocytes in affected areas of the skin. Aim:To assess and compare the clinical efficacy of Mitrapanchaka Yoga withand without Avalgujbeejadi lepa inthe management of Shwitra (Vitiligo).Material and methods: In this trial, 34 patients were registered, out of which 30completed the treatment. Patients were randomly divided in twogroups with the help of computer generated random selection method viz. Group Aand Group B. In Group A classical Mridu Samshodhana was given followed by oral administration of Mitrapanchaka Yoga as a Shamana Yoga, followed by Avalgujbeejadilepa for local application. InGroup B patients were treated with MriduSamshodhana followed by oral administration of Mitrapanchaka Yogainternally. Special scoring pattern was adopted forscrutinizing the symptomatology. The score was given on the basis of Size,Colour, Number of patches, percentage of body area involvement and chronicityof patches. VASI Score toknow overall effect of therapy on two groups and VIS-22 Score for each patientwas calculated **Results:**On Applying VASI Score both groups showedhighly significant results.VIS-22 Score was suggestive of high psychologicalinvolvement in disease. **Conclusion:**Oncomparison group A showed better results in percentage changes, resultdifference was significant in improvement in number of patches in Group A, which suggeststhat Mitrapanchaka Yoga and Avalgujabeejadi Lepa together givebetter results than Mitrapanchaka Yoga alone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 16.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having signs and symptoms of Shwitra (vitiligo).
- •Patients between age group of 16 years to 60 years will be selected.
排除标准
- •1.Patients having chronic condition, more than 10 years 2.Patients having all other de-pigmentory disorders.
- •3.Patients having serious cardiac, renal, hepatic diseases.
- •4.Patients having major illness like IDDM, NIDDM which are poorly controlled and any other systemic diseases.
- •5.Patches due to burning, chemical explosion etc.
- •6.Located at region of Guhya (Genital region), Panitala (Foot soals and Hand soals), Oshtha (Lips), Aekanga, Sarvanga(whole body).
- •7.Patches with Raktaloma, Sansakta Mandala.
结局指标
主要结局
will be evaluated
时间窗: will be evaluated after 60 days
次要结局
- will be evaluated(will be evaluated after 60 days)