Comparison of haemodynamic response with three different techniques of endotracheal intubation in patients undergoing craniotomy under general anaesthesia
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/01/061674
- Lead Sponsor
- Bangur Institute of Neurology, IPGME&R and SSKM Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients belonging to ASA grades- I, II and III
2. Patients undergoing elective craniotomies for non- vascular intracranial lesions
Exclusion Criteria
1. Patients having anticipated difficult airways
2. Patients having hypertension or diabetes mellitus
3. Patients on any drug known to affect heart rate and blood pressure
4. Patient refusal to participate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare heart rate and blood pressure changes triggered by the three different techniques of endotracheal intubation- direct laryngoscopy, Kingvision® chanelled video laryngoscopy, Blockbuster® LMA guided technique.Timepoint: primary outcome variables will be measured at the following time points: <br/ ><br>1. Baseline <br/ ><br>2. Following neuromuscular blockade <br/ ><br>3. Immediately after endotracheal intubation <br/ ><br>4. 4 more readings at 1 minute intervals starting from the previous recording
- Secondary Outcome Measures
Name Time Method 1. To compare the number of intubation attempts between the three groups <br/ ><br>2. To compare the additional manipulations required for intubation in the three groups <br/ ><br>3. To study the glottic view (Cormack–Lehane) <br/ ><br>4. To record traumatic complications caused by intubation procedure <br/ ><br>Timepoint: 1st, 2nd & 3rd outcome to be measured at single time point during endotracheal intubation. 4th outcome will be measured immediately postoperatively in the recovery room or IC