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Study on Brain Network of Antidepressant Effect Mechanism with Acupuncture

Phase 1
Recruiting
Conditions
Depression
Registration Number
ITMCTR1900002656
Lead Sponsor
Guangdong Province Traditional Chinese Medical Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Participants who meet the diagnostic criteria of Depressive Disorder Due to Another Medical Condition according to DSM – 5 from the American psychiatric association,and the level of depression conforms to moderate to mild depression (F32.0) or moderate depression (F32.1) according to the International Classification of Diseases Coding Table (ICD-10) or whose HAMD-17 score 8-22;
2. Participants was diagnosed with a first appearance depressive disorder;
3. Participants who have not received hormone replacement therapy or anti-depression medication within 3 months;
4. Participants aged 18 to 40 years;
5. Willingness to participate in the trial and having provided written consent.

Exclusion Criteria

1. Item 4 or 5 of Beck Suicide Ideation Scale (SSI) is not answered No;
2. The depression factors in SCL-90 score failed to exclude the suicidal tendency (>26);
3. Participants had participated in other clinical trials within 4 weeks before the start of this study;
4. Participants who had severe diseases of other systems require treatment;
5. Participants had brain diseases and judgment ability was abnormal (Wechsler Adult Intelligence Scale<90);
6. Desiring to conceive,pregnant or lactating women;
7. Participants who had been taking anti-depression and anti-anxiety medication for 2 weeks before the trial;
8. Participant who install a pacemaker or an artificial joint.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
HAMD-17;
Secondary Outcome Measures
NameTimeMethod
Electroencephalogram;
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