brain connectivity and neurotransmitter in depressio

Not Applicable

Recruiting

• Conditions: Mental and behavioural disorders

• Registration Number: KCT0008168
• Lead Sponsor: The Catholic University of Korea, St. Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

Adult men and women between the ages of 19 and 75
- Patients diagnosed as depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders - 5th Edition (DSM-V) and showing depressive symptoms of less than moderate severity (BDI 14-28 points)

Exclusion Criteria

- Patients with a history of diagnosis or coexistence of a psychotic disorder, including bipolar disorder, schizophrenia, schizoaffective disorder, schizophrenic disorder, or psychotic disorder not otherwise classified
- Patients with psychotic symptoms among major depressive disorders
- Patients with organic mental disorder, epilepsy or convulsive disorder
- Uncontrolled medical conditions (e.g., diseases of the kidney, liver, cardiovascular, respiratory, cerebrovascular, endocrine, immune system)
- Patients with other serious acute physical illnesses who are difficult to maintain psychiatric evaluation and treatment
- Patients who currently require inpatient treatment for psychiatric disorders other than depression (e.g., alcohol dependence, drug abuse)
- Patients at high risk of suicide, self-harm, and other harm
- Patients whose history of treatment for current depressive episode is unclear
- A history of brain surgery and magnetic material inserted into the head or eye
- If you have a history of severe wasting disease such as uncontrolled thyroid disease, liver disease, or kidney disease
- Wearing a pacemaker, infusion pump, and hearing aid
- Patients who do not understand or do not agree to the contents of the study
- Patients judged unsuitable by researchers

Study & Design

• Study Type: Observational Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain connectivity

Secondary Outcome Measures

Name	Time	Method
HADS-A (Hospital Anxiety and Depression Scale);dopamine, serotonin, cortisol;CERAD-K score;Korean version of perceived stress scale, K-PSS;HRV(Heart Rate Variability);Beck Depression Inventory score;Maudsley Obsessive Compulsive Inventory (MOCI)