Intestinal-brain association of depression,Imaging metabolomics Research
Not Applicable
- Conditions
- Depression
- Registration Number
- JPRN-UMIN000043901
- Lead Sponsor
- Showa University School of Medicine Department of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
Participants with dementia. Participants with gastro intestinal disorder. Participants who are receiving the antibiotic treatment. Participants who can not agree with collecting faces samples or with taking the brain MRI.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feces samples will be collected at least three times.Bacterial metagenome and metabolomics will be assessed with 16SrRNA methodology and Mass spectrometry.
- Secondary Outcome Measures
Name Time Method Original questionnaire of lifestyles Brief-type self-administered Diet History Questionnaire Hamilton Depression Rating Scale Hamilton Anxiety Scale Montgomery-Asberg Depression Ratin g Scale Pittsburgh Sleep Quality Index Gastrointestinal Symptom Rating Scale Original questionnaire of Gastrointestinal Symptom fMRI