Physical exercise program as an adjuvant therapy for hematopoietic stem cell transplantation: a pilot study
- Conditions
- (non) Hodgkin's diseasehematopoietische maligniciesKahler's diseasesleukemia1002432410025319
- Registration Number
- NL-OMON34271
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
- Diagnosed with acute or chronic leukemia, Hodgkin*s Lymphoma, non-Hodgkins*s Lymphoma or Multiple Myeloma;
- Scheduled to undergo an allogenic or autologous HSCT;
- No cardiovascular contra-indication to engage in physical activity programs as checked by the Physical Activities Readiness Questionnaire (PAR-Q) (Thomas et al 1992), and/or no other physical limitations for physical exercise programs;
- Sufficient knowledge of the Dutch language;
- Approval to participate in the study by the treating physician, and
- Being aged in the age range 18 years through 65 years
Cardiovascular or other contra-indications (e.g. rheumatic disease) for participating in a physical exercise program. Decisions to exclude potential participants will be made based on the results of the Physical Activities Readiness Questionnaire (PAR-Q) and after consultation with the physician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome of this study is self-perceived physical functioning<br /><br>(subscale of SF-36 questionnaire). </p><br>
- Secondary Outcome Measures
Name Time Method <p>Global perceived recovery (7-points Likert-scale), tiredness (CIS-20<br /><br>questionnaire), Quality of life (SF-36 questionnaire), incidence of oral and<br /><br>lung infections (patient files), length of hospital stay, V02 max (submaximal<br /><br>bicycle test), muscle strength of large muscle groups (dynamometer), and<br /><br>lymphocyte count.</p><br>