To Compare Two Local Anesthetic Drugs In Minor Oral Surgical Procedures.

Phase 4

Completed

• Conditions: Impacted teeth, (2) ICD-10 Condition: K088||Other specified disorders of teethand supporting structures,

• Registration Number: CTRI/2019/03/018170
• Lead Sponsor: Vishwajeet Singh Jamwal

Brief Summary

Ropivacaine hydrochloride being a long acting amide  local anesthetic having long duration ( 6-7 hours) of action can be beneficial in minor oral surgical procedures like surgical extraction of impacted teeth , enucleation of small cysts ,fracture reduction ,intermaxillary fixation etc.These procedures are routinely carried out under local anesthesia but require repeated infiltration or nerve blocks with more conventional drug i.e Lignocaine hydrochloride with 1:200000 adrenaline having moderate duration of action ranging from 120-150 minutes. In patients with CVS problems in whom adrenaline is contraindicated and plain Lignocaine without vasoconstrictor fails to provide effective anesthesia for required duration , Ropivacaine hydrochloride can provide effective anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-03-20
• Study Completion: 2021-01-22
• Last Update Posted: 2021-06-26

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

• Patients not receiving any medications that will alter the perception of pain.
• Patients requiring extraction of bilaterally symmetrical teeth.

Exclusion Criteria

• 1.Patients with history of allergic reactions to LA of amide group and sulfides.
• 2.Patients with acute infections.
• 3.Patients taking medications like MAO inhibitors, tricyclic antidepressants , phenothiazines ,vasodepressor drugs 4.Pregnant and lactating patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset and duration of anesthesia and analgesia, Cardiovascular effects,VAS pain score.	Preoperatively, | Intraoperatively at 5 minutes interval and postoperatively as required.

Secondary Outcome Measures

Name	Time	Method
Number of additional blocks /infiltration required or any other adverse effect.

Trial Locations

Locations (1)

Dr. Harvansh Singh Judge Institute Of Dental Sciences and Hospital ,Panjab University , Chandigarh; 🇮🇳 Chandigarh, CHANDIGARH, India

Dr. Harvansh Singh Judge Institute Of Dental Sciences and Hospital ,Panjab University , Chandigarh

🇮🇳Chandigarh, CHANDIGARH, India

Vishwajeet Singh Jamwal

Principal investigator

9149774489

vish1806singh@gmail.com