A Randomized Clinical Trial Comparing 0.75% Ropivacaine And 2% Lignocaine With 1 : 200000 Adrenaline In Minor Oral Surgery.
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 128
- Locations
- 1
- Primary Endpoint
- Onset and duration of anesthesia and analgesia, Cardiovascular effects,VAS pain score.
Study Overview
Brief Summary
Ropivacaine hydrochloride being a long acting amide local anesthetic having long duration ( 6-7 hours) of action can be beneficial in minor oral surgical procedures like surgical extraction of impacted teeth , enucleation of small cysts ,fracture reduction ,intermaxillary fixation etc.These procedures are routinely carried out under local anesthesia but require repeated infiltration or nerve blocks with more conventional drug i.e Lignocaine hydrochloride with 1:200000 adrenaline having moderate duration of action ranging from 120-150 minutes. In patients with CVS problems in whom adrenaline is contraindicated and plain Lignocaine without vasoconstrictor fails to provide effective anesthesia for required duration , Ropivacaine hydrochloride can provide effective anesthesia.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 14.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients not receiving any medications that will alter the perception of pain.
- •Patients requiring extraction of bilaterally symmetrical teeth.
Exclusion Criteria
- •1.Patients with history of allergic reactions to LA of amide group and sulfides.
- •2.Patients with acute infections.
- •3.Patients taking medications like MAO inhibitors, tricyclic antidepressants , phenothiazines ,vasodepressor drugs 4.Pregnant and lactating patients.
Outcomes
Primary Outcomes
Onset and duration of anesthesia and analgesia, Cardiovascular effects,VAS pain score.
Time Frame: Preoperatively, | Intraoperatively at 5 minutes interval and postoperatively as required.
Secondary Outcomes
- Number of additional blocks /infiltration required or any other adverse effect.