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临床试验/CTRI/2026/04/107822
CTRI/2026/04/107822尚未招募不适用

EFFECT OF PERIODONTAL THERAPY ON BLOOD PRESSURE LEVELS,SERUM C-REACTIVE PROTEIN AND LIPID PROFILE IN HYPERTENSIVE PATIENTS WITH STAGE III PERIODONTITIS-A CLINICO HEMATOLOGICAL STUDY

Dr SWATHI S MALAGATTI1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2026年8月28日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
35
试验地点
1

研究概览

简要总结

This clinico-hematological study will be conducted among patients aged over 18 years with known hypertension and Stage III periodontitis.The primary objective is to evaluate and compare the effectiveness of non-surgical periodontal therapy (scaling and root planing) and surgical periodontal therapy (flap surgery) on clinical periodontal parameters, blood pressure, serum C-reactive protein (CRP), and lipid profile in hypertensive patients with Stage III periodontitis.Eligible participants will undergo baseline assessment, including plaque index, gingival index, bleeding on probing, probing pocket depth, clinical attachment level, blood pressure measurement, and blood investigations for CRP and lipid profile. All patients will initially receive scaling and root planing. After 2 weeks, clinical and biochemical parameters will be reassessed. Patients with persistent periodontal pockets will then undergo flap surgery and will be re-evaluated at 3 months.The study aims to determine whether surgical therapy provides additional systemic and periodontal benefits compared to non-surgical treatment and to analyze changes in inflammatory markers and cardiovascular risk indicators over time.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Patients of age more than 18 years 2) Patients with known hypertension 3) Patients with stage III Periodontitis (probing depth greater than or equal to 6mm) 4) Patients with radiographic evidence of bone loss.

排除标准

  • (1) active infectious diseases, such as hepatitis, HIV, or tuberculosis, (2) pregnant or breastfeeding, and (3) taking nonsteroidal anti-inflammatory drugs on a regular basis or taking antibiotics within 3 months of assessment.

研究者

发起方
Dr SWATHI S MALAGATTI
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

DrSwathi S Malagatti

COORG INSTITUTE OF DENTAL SCIENCES

研究点 (1)

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