Relationship Between Tissue Markes in Patients With Post Cardio Respiratory Syndrome

• Conditions: Cardiac Arrest

• Registration Number: NCT01455662
• Lead Sponsor: Hospital Nossa Senhora da Conceicao

Brief Summary

There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.

Detailed Description

Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).

Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p \<0.05).

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2011-09-28
• Study First Submitted QC: 2011-10-19
• Study First Posted: 2011-10-20
• Status Verified: 2011-11
• Last Update Submitted: 2011-11-02
• Last Update Posted: 2011-11-03
• Primary Completion: 2011-12
• Study Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace

Exclusion Criteria

pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.

• patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest
• less 18 years old

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mortality	1 year

Secondary Outcome Measures

Name	Time	Method
correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance	6 hours

Trial Locations

Locations (1)

Conceição Hospital; 🇧🇷 Porto Alegre, Rio Grande do Sul, Brazil