Postoperative Lactate and Atrial Fibrillation After CABG
- Conditions
- Coronary Artery DiseaseAtrial Fibrillation
- Registration Number
- NCT05448521
- Lead Sponsor
- Başakşehir Çam & Sakura City Hospital
- Brief Summary
Postoperative atrial fibrillation (POAF) is associated with increased mortality and morbidity in patients undergoing isolated coronary artery bypass grafting (CABG). It has been estimated that 5-40% of CABG patients experience POAF. Advanced age, P wave abnormalities, left atrial dilation, emergency surgery, low left ventricle ejection fraction, low glomerular filtration rate and chronic obstructive pulmonary disease have been reported in the etiology. Predicting which patients would experience POAF following CABG is important since it would allow physicians to apply more focused prophylactic measures. Lactate is the final product of anaerobic glycolysis. Serum lactate level are increased in case of inadequate oxygen delivery to tissues. The investigators aim to assess whether serum lactate levels measured early in the postoperative period could be used as a predictive marker of POAF in adults undergoing isolated CABG.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 250
- Undergoing isolated CABG
- Age >18 years
- Age <18 years
- Pregnancy
- History of paroxysmal atrial fibrillation prior to surgery
- Undergoing concomitant procedures (e.g., CABG + valve surgery)
- Any preoperative cardiac rhythm other than normal sinus rhythm
- More than mild cardiac valve stenosis or insufficiency
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative atrial fibrillation 30 days New-onset atrial fibrillation occurring in the immediate period after CABG
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Basaksehir Cam Sakura City Hospital
🇹🇷Istanbul, Turkey